Preparation of (Z)-1-halo-1-alkenes and (Z)-1-halo-2-alkoxy-1-alkenes using Cr(II/III) and Fe(0)

Reduction of 1, 1, 1-trihaloalkanes by Cr(II) or Cr(III) regenerated by Fe(0) in rnoist tetrahydrofuran at room temperature stereoselectively generates (Z)-1-halo-1-alkenes and (Z)-1-halo-2alkoxy-1-alkenes in good to excellent yields.

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Bibliographic Details
Published inSynlett no. 16; pp. 2652 - 2654
Main Authors Falck, J. R., He, Anyu, Bejot, Romain, Mioskowski, Charles
Format Journal Article
LanguageEnglish
Published STUTTGART Thieme Medical Publishers 04.10.2006
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Summary:Reduction of 1, 1, 1-trihaloalkanes by Cr(II) or Cr(III) regenerated by Fe(0) in rnoist tetrahydrofuran at room temperature stereoselectively generates (Z)-1-halo-1-alkenes and (Z)-1-halo-2alkoxy-1-alkenes in good to excellent yields.
ISSN:0936-5214
DOI:10.1055/s-2006-951467