Index Development to Comprehensive Assess Liver Function during the Dairy Cows' Transition Period in Low-Tropic Conditions

The aim of this work was to develop a liver tissue function index during the transition period of dairy cows managed in low-tropic conditions. In two farms, twenty crossbred and synthetic native cows during the peripartum period were selected, and blood samples were taken on days -30 and -15 prepart...

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Published inAnimals (Basel) Vol. 14; no. 14; p. 2056
Main Authors Campos-Gaona, Rómulo, Correa-Orozco, Adriana, Salamanca-Carreño, Arcesio, Vélez-Terranova, Mauricio
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 13.07.2024
Subjects
Animals
Biomarkers
bovine
Classification
Cluster analysis
Dairy cattle
Energy
Enzymes
Fatty acids
hepatic function index
Homeostasis
Ketosis
Liver
Metabolism
Metabolites
Milk production
Proteins
transition period
Variables
hepatic function index
bovine
transition period
metabolism
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Summary:The aim of this work was to develop a liver tissue function index during the transition period of dairy cows managed in low-tropic conditions. In two farms, twenty crossbred and synthetic native cows during the peripartum period were selected, and blood samples were taken on days -30 and -15 prepartum, the calving day, and 7, 20, 35, 50, 65, 80 and 105 days postpartum for serum metabolic tests. On each measurement day, body condition scores (BCS) and parameters on nitrogen metabolism (total protein-TP, albumin-ALB, globulin-GLOB, urea), adipose tissue metabolism (cholesterol-COL, non-esterified fatty acids-NEFA) and two transaminases (alanine aminotransferase-ALT and aspartate aminotransferase-AST) were evaluated. Data analysis included the Spearman correlation, principal components, multiple linear regression and cluster analysis. Results showed that regarding the days after calving and BCS, a liver tissue function index can be constructed using the TP, urea, COL, ALT and NEFA. The estimated index generated three groupings, both by days after calving and BCS. In the former, the index discriminated the metabolic behavior in the prepartum, parturition and postpartum periods, while in the latter, the index discriminated between extreme (2.25, 2.50 and 4.25), slightly low (2.75 and 3.0) and slightly high (3.25 to 4) conditions. The results allow us to conclude that it is feasible to construct mathematical function indexes for liver function to monitor metabolic changes during highly demanding productive phases in dairy cows under tropical conditions.
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ISSN:2076-2615
2076-2615
DOI:10.3390/ani14142056