D-lactic acidosis in humans: review of update

D-Lactic acidosis has been well documented in ruminants. In humans, D-lactic acidosis is very rare, but D-lactic acidosis may be more common than generally believed and should be looked for in a case of metabolic acidosis in which the cause of acidosis is not apparent. The clinical presentation of D...

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Published inElectrolyte & blood pressure : E & BP Vol. 4; no. 1; pp. 53 - 56
Main Authors Kang, Kyung Pyo, Lee, Sik, Kang, Sung Kyew
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Society of Electrolyte and Blood Pressure Research 01.03.2006
Subjects
Review
D-lactic acidosis
Humans
Metabolic acidosis
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Summary:D-Lactic acidosis has been well documented in ruminants. In humans, D-lactic acidosis is very rare, but D-lactic acidosis may be more common than generally believed and should be looked for in a case of metabolic acidosis in which the cause of acidosis is not apparent. The clinical presentation of D-lactic acidosis is characterized by episodes of encephalopathy and metabolic acidosis. The entity should be considered as a diagnosis in a patient who presents with metabolic acidosis accompanied by high anion gap, normal lactate level, negative Acetest, history of short bowel syndrome or malabsorption, and characteristic neurologic manifestations. Low carbohydrate diet, bicarbonate treatment, rehydration, and oral antibiotics would be helpful in controlling symptoms.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:1738-5997
2092-9935
DOI:10.5049/EBP.2006.4.1.53