Reaction of electron-deficient N-sulfinylanilines with chiral α-hydroxy acids: a new process for the synthesis of enantiomerically pure α-hydroxy amides

A practical procedure to prepare enantiomerically pure α-hydroxy amides from chiral α-hydroxy acids and electron-deficient anilines via N-sulfinylaniline derivatives has been developed.

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 41; no. 32; pp. 6017 - 6020
Main Authors Chidambaram, Ramakrishnan, Zhu, Jason, Penmetsa, Kumar, Kronenthal, David, Kant, Joydeep
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 2000
Elsevier
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
FACILE SYNTHESIS
Online AccessGet full text

Cover

More Information
Summary:A practical procedure to prepare enantiomerically pure α-hydroxy amides from chiral α-hydroxy acids and electron-deficient anilines via N-sulfinylaniline derivatives has been developed.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(00)01011-X