Synthesis of substituted 3-trifluoromethylbenzo[ b]thiophenes

A straightforward method for the synthesis of 5/6-substituted 3-trifluoromethylbenzo[ b]thiophenes and their precursor o-fluorinated trifluoro acetophenones is reported. Graphic

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Bibliographic Details
Published inTetrahedron letters Vol. 44; no. 38; pp. 7147 - 7149
Main Author Owton, W.M.
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 15.09.2003
Elsevier
Subjects
Chemistry
Chemistry, Organic
lithiation
Physical Sciences
Science & Technology
trifluoromethylbenzothiophenes
trifluoromethylbenzothiophenes
lithiation
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Summary:A straightforward method for the synthesis of 5/6-substituted 3-trifluoromethylbenzo[ b]thiophenes and their precursor o-fluorinated trifluoro acetophenones is reported. Graphic
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(03)01811-2