Stereocontrolled glycosylation of sordaricin in the presence of ammonium salts

The glycosidation of sordaricin with deoxy sugars derivatives was studied under acid-promoted conditions and by anomeric O-alkylation with sordaricin triflate. In both methods, an important effect of added ammonium salts on the stereoselectivity of the glycosidation was observed.

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 41; no. 22; pp. 4373 - 4377
Main Authors Coterón, José M., Chiara, José L., Fernández-Mayoralas, Alfonso, Fiandor, José M., Valle, Nuria
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 08.06.2000
Elsevier
Subjects
antifungals
carbohydrates
Chemistry
Chemistry, Organic
glycosidation
Physical Sciences
Science & Technology
stereocontrol
carbohydrates
antifungals
glycosidation
stereocontrol
O-ALKYLATION
Online AccessGet full text

Cover

More Information
Summary:The glycosidation of sordaricin with deoxy sugars derivatives was studied under acid-promoted conditions and by anomeric O-alkylation with sordaricin triflate. In both methods, an important effect of added ammonium salts on the stereoselectivity of the glycosidation was observed.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(00)00654-7