Microwave activated solvent-free cascade reactions yielding highly functionalised 1,3-thiazines

• Published in: Tetrahedron letters Vol. 44; no. 30; pp. 5637 - 5640
• Main Authors: Yadav, Lal Dhar S., Singh, Amrish
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 21.07.2003; Elsevier
• Subjects: 1,3-thiazines; Chemistry; Chemistry, Organic; dithiocarbamates; microwaves; Physical Sciences; Science & Technology; solvent-free cascade reactions; stereoselective synthesis; microwaves; dithiocarbamates; solvent-free cascade reactions; 1,3-thiazines; stereoselective synthesis; ORGANIC-SYNTHESIS; ALDOL CONDENSATIONS; DERIVATIVES; CYCLIZATION

One-pot cascade reactions of N-acylglycines, acetic anhydride, anhydrous sodium acetate, aromatic aldehydes, and ammonium N-aryldithiocarbamates expeditiously and diastereoselectively yield 5-acylamino-3,6-diarylperhydro-2-thioxo-1,3-thiazin-4-ones ( 5a– j ) in solvent-free conditions under microwav...