A highly diastereoselective electrochemical epoxidation

The electrochemical epoxidation of 3 gives the Merck HIV-protease inhibitor, Indinavir Sulfate, intermediate 1 in high yield and diastereoselectivity in an operationally simple procedure. Electrochemical epoxidation of 3 gives the Merck HIV-protease inhibitor (Indinavir Sulfate) intermediate 1 in hi...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 38; no. 5; pp. 777 - 778
Main Authors Rossen, K., Volante, R.P., Reider, P.J.
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 03.02.1997
Elsevier
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
PROTEASE INHIBITOR
L-735,524
INTERMEDIATE
Online AccessGet full text

Cover

More Information
Summary:The electrochemical epoxidation of 3 gives the Merck HIV-protease inhibitor, Indinavir Sulfate, intermediate 1 in high yield and diastereoselectivity in an operationally simple procedure. Electrochemical epoxidation of 3 gives the Merck HIV-protease inhibitor (Indinavir Sulfate) intermediate 1 in high yield and diastereoselectivity in an operationally simple procedure.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(96)02445-8