Iron catalyzed hydrodebromination of 2-aryl-1,1-dibromo-1-alkenes
2-Aryl- or 2-heteroaryl-1,1-dibromo-1-alkenes are reduced by Grignard reagents in a THF+NMP mixture in the presence of a catalytic amount of iron salts, to afford the corresponding E vinyl bromides. Further application to the one pot reduction-cross coupling reaction with Grignard reagents is highli...
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Published in | Journal of organometallic chemistry Vol. 624; no. 1; pp. 131 - 135 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
LAUSANNE
Elsevier B.V
01.04.2001
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | 2-Aryl- or 2-heteroaryl-1,1-dibromo-1-alkenes are reduced by Grignard reagents in a THF+NMP mixture in the presence of a catalytic amount of iron salts, to afford the corresponding
E vinyl bromides. Further application to the one pot reduction-cross coupling reaction with Grignard reagents is highlighted. |
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ISSN: | 0022-328X 1872-8561 |
DOI: | 10.1016/S0022-328X(00)00934-7 |