2-Amidinylindole-3-carbaldehydes: synthesis of new tetracyclic compounds containing the pyrrolo[1,2- c]1,4-diazepine ring

2-Amidinylindol-3-carbaldehydes bearing an α-alkoxycarbonyl substituent on the cyclic-tertiary amine moiety were prepared. Pyrolysis of these amidines in diethylenglycol-monoethyl ether produced mainly a pyrrolo[1′,2′-1,2]-1,4-diazepino[5,6- b]indol-7,11-dione. A similar result was obtained starting...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron Vol. 59; no. 10; pp. 1667 - 1671
Main Authors Clerici, Francesca, Erba, Emanuela, Pocar, Donato
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 03.03.2003
Elsevier
Subjects
amidines
anthramycin
Chemistry
Chemistry, Organic
intramolecular cyclization
Physical Sciences
pyrrolo[1,2- c]-1,4-diazepine
Science & Technology
amidines
anthramycin
intramolecular cyclization
pyrrolo[1,2- c]-1,4-diazepine
pyrrolo[1,2-c]-1,4-diazepine
SIBIROMYCIN
PYRROLO<1,4>BENZODIAZEPINE ANTIBIOTICS
TOMAYMYCIN
Online AccessGet full text

Cover

More Information
Summary:2-Amidinylindol-3-carbaldehydes bearing an α-alkoxycarbonyl substituent on the cyclic-tertiary amine moiety were prepared. Pyrolysis of these amidines in diethylenglycol-monoethyl ether produced mainly a pyrrolo[1′,2′-1,2]-1,4-diazepino[5,6- b]indol-7,11-dione. A similar result was obtained starting from 2-amidinylbenzofuran-3-carbaldehyde. Graphic
ISSN:0040-4020
1464-5416
DOI:10.1016/S0040-4020(03)00146-7