Diagnosis and management of hypopituitarism

This review summarizes pituitary function, and the clinical presentation and treatment of hypopituitarism. Updates in the field include new guidelines and meta-analyses on the diagnosis and treatment of select hormone deficiencies, novel treatment options, and advances in next generation sequencing...

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Bibliographic Details
Published inCurrent opinion in pediatrics Vol. 31; no. 4; p. 531
Main Authors Yeliosof, Olga, Gangat, Mariam
Format Journal Article
LanguageEnglish
Published United States 01.08.2019
Subjects
High-Throughput Nucleotide Sequencing
Humans
Hypopituitarism - diagnosis
Hypopituitarism - therapy
Pituitary Gland - physiopathology
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Summary:This review summarizes pituitary function, and the clinical presentation and treatment of hypopituitarism. Updates in the field include new guidelines and meta-analyses on the diagnosis and treatment of select hormone deficiencies, novel treatment options, and advances in next generation sequencing technology. Hypopituitarism is defined as partial or complete loss of a single or multiple pituitary hormones. The clinical presentation of hypopituitarism varies depending on the number and severity of hormone deficiencies. Treatment involves the physiologic replacement of the individual end-organ hormone deficiencies and requires close lifelong monitoring.
ISSN:1531-698X
DOI:10.1097/MOP.0000000000000779