Nanoscaled interdigitated titanium electrodes for impedimetric biosensing

Nanoscaled interdigitated electrodes (IDEs) are developed for the purpose of being used as miniature and sensitive affinity biosensors. Because of the ease to derivatise its surface, oxidized Ti is chosen as an electrode material on a SiO 2 substrate. For proof of principle, oxidized and non-oxidize...

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Bibliographic Details
Published inSensors and actuators. B, Chemical Vol. 68; no. 1; pp. 360 - 370
Main Authors Laureyn, W, Nelis, D, Van Gerwen, P, Baert, K, Hermans, L, Magnée, R, Pireaux, J.-J, Maes, G
Format Journal Article
LanguageEnglish
Published Elsevier B.V 25.08.2000
Subjects
Immobilisation
Nanoscaled interdigitated electrodes
Silanisation
Titanium dioxide
Silanisation
Nanoscaled interdigitated electrodes
Titanium dioxide
Immobilisation
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Summary:Nanoscaled interdigitated electrodes (IDEs) are developed for the purpose of being used as miniature and sensitive affinity biosensors. Because of the ease to derivatise its surface, oxidized Ti is chosen as an electrode material on a SiO 2 substrate. For proof of principle, oxidized and non-oxidized Ti IDEs are characterised in salt solutions and the immobilisation of glucose oxidase is monitored using impedance spectroscopy. Beside transducer development and demonstration, tailored bio interfaces are a prerequisite for the development of sensitive affinity biosensors. Therefore, a characterisation of immobilisations (based on silanisations) on TiO 2 and SiO 2 is conducted. For this study, different analytical techniques are identified and evaluated. The use of these techniques will enable a thorough characterisation of immobilisation processes, ultimately leading to miniature and sensitive affinity biosensors.
ISSN:0925-4005
1873-3077
DOI:10.1016/S0925-4005(00)00489-5