Laryngeal fibrous hamartoma presenting with airway obstruction at birth

• Published in: The Journal of craniofacial surgery Vol. 24; no. 4; p. e383
• Main Authors: Kşlal, Fatih Mehmet, Acar, Mehtap, Acar, Baran, Karahan, Feryal
• Format: Journal Article
• Language: English
• Published: United States 01.07.2013
• Subjects: Airway Obstruction - congenital; Airway Obstruction - diagnosis; Airway Obstruction - pathology; Airway Obstruction - surgery; Biopsy; Diagnosis, Differential; Hamartoma - congenital; Hamartoma - diagnosis; Hamartoma - pathology; Hamartoma - surgery; Humans; Infant, Newborn; Laryngeal Diseases - congenital; Laryngeal Diseases - diagnosis; Laryngeal Diseases - pathology; Laryngeal Diseases - surgery; Laryngoscopy; Male; Respiratory Sounds - diagnosis; Respiratory Sounds - etiology
• ISSN: 1536-3732
• DOI: 10.1097/SCS.0b013e31829031fd

Hamartoma is an extremely rare congenital malformation of the larynx. Hamartomas of the nasal cavity or nasopharynx are classified as epithelial, mesenchymal, and mixed epithelial and mesenchymal types. Presenting symptoms result from airway obstruction and may include slowly rising respiratory distress, stridor, changes in voice, eating, and activity levels. We present a 1-day-old newborn with a history of stridor and respiratory distress caused by a polypoid mass on the anterior half of the left ventricular band. We performed an excisional biopsy under direct laryngoscopy. Histopathologic finding after excisional biopsy was consistent with hamartoma. We report and discuss the pathological features and differential diagnosis of this rare laryngeal hamartoma. To our knowledge, laryngeal hamartoma presenting with stridor has not been described in the literature thus far.