Primary and secondary toxicity of warfarin, sodium monofluoroacetate, and methyl parathion in mink

• Published in: Archives of environmental contamination and toxicology Vol. 16; no. 3; pp. 357 - 366
• Main Authors: Aulerich, R.J, Ringer, R.K, Safronoff, J
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer-Verlag 01.05.1987; Berlin; New York, NY
• Subjects: Animals; Biological and medical sciences; Environmental pollutants toxicology; Female; Fluoroacetates - toxicity; General aspects; INSECTICIDAS; INSECTICIDE; INSECTICIDES; Lethal Dose 50; Male; Medical sciences; Methyl Parathion - toxicity; Mink - physiology; MINKS; Parathion - analogs & derivatives; PESTICIDE; PESTICIDES; PLAGUICIDAS; Rodenticides - toxicity; TOXICIDAD; TOXICITE; TOXICITY; Toxicology; VISON; WARFARIN; Warfarin - toxicity; WARFARINA; WARFARINE; Fissipedia; Carnivora; Toxicity; Pesticides; Rodenticide; Contamination; Trophic chain; Pollutant; Vertebrata; Mammalia; Lethal dose 50; Animal; Environment; Mustela furo; Food
• ISSN: 0090-4341; 1432-0703
• DOI: 10.1007/BF01054954

Mink feeding trials with warfarin, sodium monofluoroacetate and methyl parathion were conducted to investigate the primary and secondary toxicity of these compounds. Mink fed warfarin-contaminated rabbit did not exhibit secondary toxicity perhaps because warfarin may be readily bound and/or metabolized in non- or less toxic metabolites by a primary consumer. Tests for secondary toxicity of sodium monofluoroacetate were discontinued because lethal concentrations of the compound for mink could not be produced by feeding mink carcasses of rabbits. The methyl parathion LC50 tests were abandoned after 12 days of exposure because in both primary and secondary tests the mink rejected the treated feed.