Chiral derivatives of semisquaric acid as new modular ligands for asymmetric catalysis

A family of enantiomerically pure ligands based on the cyclobutenedione structure, and containing either an enantiomerically pure amino alcohol or a diamine as the chiral element, has been synthesized. As first examples of their application, these versatile and modularly constructed ligands have bee...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron: asymmetry Vol. 14; no. 12; pp. 1747 - 1752
Main Authors Ferrer, Sı́lvia, Pastó, Mireia, Rodrı́guez, Belén, Riera, Antoni, Pericàs, Miquel A.
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 20.06.2003
Elsevier
Subjects
Chemistry
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Chemistry, Physical
Physical Sciences
Science & Technology
REDUCTION
AMINO ALCOHOL
MONOAMINOALCOHOLS
MOLECULAR RECOGNITION
RUTHENIUM COMPLEXES
TRANSFER HYDROGENATION
ENANTIOSELECTIVE ADDITION
PROCHIRAL KETONES
SQUARAMIDO-BASED RECEPTORS
SQUARIC ACID
Online AccessGet full text

Cover

More Information
Summary:A family of enantiomerically pure ligands based on the cyclobutenedione structure, and containing either an enantiomerically pure amino alcohol or a diamine as the chiral element, has been synthesized. As first examples of their application, these versatile and modularly constructed ligands have been tested in the transfer hydrogenation of acetophenone and in the reduction using borane of this same substrate. Graphic
ISSN:0957-4166
1362-511X
DOI:10.1016/S0957-4166(03)00355-0