Synthesis of 2-heterosubstituted quinazolinone atropisomeric phosphine ligands by direct lithiation of a 2-unsubstituted quinazolinone system

The syntheses of 2-heterosubstituted atropisomeric quinazolinone phosphine ligands 7e– g have been achieved in good yield by the straightforward direct lithiation of the 2-unsubstituted quinazolinone ligand 7d followed by electrophilic substitutions.

Saved in:
Bibliographic Details
Published inTetrahedron: asymmetry Vol. 10; no. 1; pp. 25 - 29
Main Authors Dai, Xuedong, Virgil, Scott
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 15.01.1999
Elsevier
Subjects
Chemistry
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Chemistry, Physical
Physical Sciences
Science & Technology
CATALYSIS
PALLADIUM COMPLEXES
METAL-COMPLEXES
RESOLUTION
Online AccessGet full text

Cover

More Information
Summary:The syntheses of 2-heterosubstituted atropisomeric quinazolinone phosphine ligands 7e– g have been achieved in good yield by the straightforward direct lithiation of the 2-unsubstituted quinazolinone ligand 7d followed by electrophilic substitutions.
ISSN:0957-4166
1362-511X
DOI:10.1016/S0957-4166(98)00496-0