Separation and identification of phenothiazine compounds by thin-layer chromatography

The chromatographic behavior of phenothiazine derivatives is studied by thin-layer chromatography with the use of Sorbfil silica gel plates in a binary benzene-methanol mixture of solvents. An empirical equation describing the dependence of the retention value (mobility Rf) of the substance on the p...

Full description

Saved in:
Bibliographic Details
Published inJournal of analytical chemistry (New York, N.Y.) Vol. 61; no. 1; pp. 2 - 5
Main Authors Temerdashev, Z. A., Kiseleva, N. V., Klishchenko, R. A., Udalov, A. V.
Format Journal Article
LanguageEnglish
Published New York Springer 01.01.2006
Springer Nature B.V
Subjects
Analysis
Benzene
Chemical properties
Chromatography
Empirical equations
Ions
Mathematical analysis
Phenothiazine
Silica gel
Thin layer chromatography
Online AccessGet full text

Cover

More Information
Summary:The chromatographic behavior of phenothiazine derivatives is studied by thin-layer chromatography with the use of Sorbfil silica gel plates in a binary benzene-methanol mixture of solvents. An empirical equation describing the dependence of the retention value (mobility Rf) of the substance on the physicochemical properties of the eluent is proposed. The effect of interactions of different types on the value of their chromatographic retention is estimated; the relation of the obtained coefficients of equations for the substances under study is analyzed. The obtained empirical dependences are used to calculate the Rf values. The discrepancy between the calculated and experimental data is below 0.07.
ISSN:1061-9348
1608-3199
DOI:10.1134/S1061934806010023