Palladium (II) catalysed oxime-metallo-nitrone-isoxazolidine cascade reactions of α-imino aldoximes

Palladium (II) salts catalyse stereospecific and highly facially selective oxime-nitrone-isoxazolidine cascade reactions between α-imino aldoximes and N-methylmaleimide via intermediate N-metallo-aldonitrones. These processes occur at room temperature in a range of polar solvents through the chelati...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 38; no. 44; pp. 7777 - 7780
Main Authors Frederickson, Martyn, Grigg, Ronald, Thornton-Pett, Mark, Redpath, James
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 03.11.1997
Elsevier
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
CYCLOADDITION
Online AccessGet full text

Cover

More Information
Summary:Palladium (II) salts catalyse stereospecific and highly facially selective oxime-nitrone-isoxazolidine cascade reactions between α-imino aldoximes and N-methylmaleimide via intermediate N-metallo-aldonitrones. These processes occur at room temperature in a range of polar solvents through the chelation of both α-imino and aldoxime nitrogen atoms to the palladium (II) centre. Palladium (II) salts catalyse stereospecific and highly facially selective oxime-nitrone-isoxazolidine cascade reactions between α-imino aldoximes and N-methylmaleimide via intermediate N-metallo-aldonitrones. These processes occur at room temperature in a range of polar solvents through the chelation of both α-imino and aldoxime nitrogen atoms to the palladium (II) centre.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(97)01816-9