NMR and CD studies of sulfur chirality center in Pd(II) complexes with S-benzyl-cysteine and glycyl-S-benzyl-L-cysteine

1H NMR and CD spectra have shown the creation of chirality centers on thioether sulfur atoms when bound to metal ions in Pd(II) complexes with S-benzyl-L-cysteine and glycyl-S-benzyl-L-cysteine. Two diastereomers are formed with R or S configuration on the sulfur. The 1H NMR and CD spectra as well a...

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Bibliographic Details
Published inInorganica Chimica Acta Vol. 78; pp. 31 - 35
Main Authors Kozłowski, Henryk, Decock-Le-Reverend, Brigitte, Delaruelle, Jean-Luc, Loucheux, Claude, Ancian, Bernard
Format Journal Article
LanguageEnglish
Published Elsevier B.V 1983
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Summary:1H NMR and CD spectra have shown the creation of chirality centers on thioether sulfur atoms when bound to metal ions in Pd(II) complexes with S-benzyl-L-cysteine and glycyl-S-benzyl-L-cysteine. Two diastereomers are formed with R or S configuration on the sulfur. The 1H NMR and CD spectra as well as the molecular model considerations were used to suggest the absolution configuration of the respective diastereomers in the series of Pd(II) complexes with S-methyl, S-ethyl and S-benzyl-L-cysteine derivatives. The S-substituent was also found to have a critical influence on the absolute configuration of sulfur atom in the studied complexes.
ISSN:0020-1693
1873-3255
DOI:10.1016/S0020-1693(00)86484-1