Myocardial motion-corrected phase-sensitive inversion recovery late gadolinium enhancement in free breathing paediatric patients: a comparison with single-shot coherent gradient echo (“TrueFISP”) phase-sensitive inversion recovery

• Published in: Clinical radiology Vol. 76; no. 6; pp. 471.e17 - 471.e25
• Main Authors: Xie, L.J., Xu, R., Xu, Z.Y., Li, X.S., Zhou, X.Y., Bi, X.M., Mu, J.S., Fan, H.M., Xu, H.Y., Guo, Y.K.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2021
• ISSN: 0009-9260; 1365-229X
• DOI: 10.1016/j.crad.2021.01.018

To investigate the value of motion-corrected (MOCO) phase-sensitive inversion recovery (PSIR) late gadolinium enhancement (LGE) compared with single-shot balanced steady-state gradient echo (“TrueFISP”, Siemens) PSIR in free breathing paediatric patients. In this retrospective study, 238 paediatric patients underwent clinical contrast-enhanced cardiovascular magnetic resonance imaging (CMRI). Both the single-shot TrueFISP PSIR and MOCO PSIR sequences were performed on each child. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Two radiologists rated the quality of the images on a scale of 1–5 (1 = poor, 5 = very good). Bland–Altman, linear regression, and intraclass correlation coefficient were used to compared the extent of LGE of the single-shot TrueFISP PSIR and MOCO PSIR. Imaging artefacts were described and compared. Children ranged in age from 60 days to 17 years with an average age of 8.1 ± 3.8 years. MOCO PSIR had higher SNR and CNR than the single-shot TrueFISP PSIR (p<0.001). Mean quality ratings for short-axis imaging were 4 (interquartile range, 3–4) for single-shot TrueFISP PSIR and 4 (interquartile range, 4–5) for MOCO PSIR (p<0.001). The scan time was faster for single-shot TrueFISP PSIR than for MOCO PSIR. The myocardial LGE results were similar with high agreement between the single-shot TrueFISP PSIR and MOCO PSIR (ICC = 0.955–0.986). The MOCO PSIR sequence is feasible in children. MOCO PSIR is robust at high heart rates and can be performed without breath-holding with higher image-quality ratings than the single-shot TrueFISP PSIR. •Acquisition times of PSIR MOCO is longer than single-shot TrueFISP PSIR.•MOCO PSIR can significantly improve image quality and reduce artifact.•LGE quantification was similar between the single-shot TrueFISP PSIR and MOCO PSIR.