Efficient synthesis of novel pyrido[3,2- d]pyrimidine-2,4-diones

A series of pyrido[3,2- d]pyrimidine-2,4-diones 5a– g have been synthesized through conversion of 2,3-pyridinedicarboxylic anhydride 1 into half-ester 2 , subsequent Curtius rearrangement and further reaction with amino acids. Graphic

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Bibliographic Details
Published inTetrahedron letters Vol. 44; no. 13; pp. 2745 - 2747
Main Authors Mamouni, R, Aadil, M, Akssira, M, Lasri, J, Sepulveda-Arques, J
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 24.03.2003
Elsevier
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:A series of pyrido[3,2- d]pyrimidine-2,4-diones 5a– g have been synthesized through conversion of 2,3-pyridinedicarboxylic anhydride 1 into half-ester 2 , subsequent Curtius rearrangement and further reaction with amino acids. Graphic
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(03)00273-9