Synthetic approach to tricyclic β-lactams using metathesis and Diels–Alder reactions

A family of functionalised tribactams has been prepared using a new approach. The two main steps are an intramolecular metathesis reaction and a Diels–Alder cyclisation. Graphic

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Bibliographic Details
Published inTetrahedron letters Vol. 42; no. 13; pp. 2461 - 2464
Main Authors Duboc, Romain, Hénaut, Charlotte, Savignac, Monique, Genet, Jean-Pierre, Bhatnagar, Neerja
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 26.03.2001
Elsevier
Subjects
Chemistry
Chemistry, Organic
cyclisation
Diels–Alder
metathesis
Physical Sciences
Science & Technology
tribactams
tribactams
cyclisation
Diels–Alder
metathesis
1-BETA-METHYLCARBAPENEM
GV104326
COMPLEXES
INTERMEDIATE
Diels-Alder
CARBAPENEM ANTIBIOTICS
IN-VITRO ACTIVITY
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Summary:A family of functionalised tribactams has been prepared using a new approach. The two main steps are an intramolecular metathesis reaction and a Diels–Alder cyclisation. Graphic
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(01)00177-0