Kinetic resolutions: evaluation of a one dimensional E value calculation method using a computer and statistical software

A recently published curve fitting method of determining E values was put to the test using a computer and statistical software. Using idealized data and curves, the methodology worked reasonably well. Confidence limits generated by the ideal data were still large. However, when real data were emplo...

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Bibliographic Details
Published inTetrahedron: asymmetry Vol. 8; no. 8; pp. 1153 - 1156
Main Authors Zmijewski, Milton J, Sullivan, Gary, Persichetti, Rose, Lalonde, Jim
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 24.04.1997
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Summary:A recently published curve fitting method of determining E values was put to the test using a computer and statistical software. Using idealized data and curves, the methodology worked reasonably well. Confidence limits generated by the ideal data were still large. However, when real data were employed, this methodology was not satisfactory in generating reliable E values due to inherent errors in the progress curves generated. This approach does not appear to be suitable for determining E values from one dimensional progress curves even when powerful statistical software and a computer are used to evaluate the data. Graphic
ISSN:0957-4166
1362-511X
DOI:10.1016/S0957-4166(97)00112-2