Remote O, C-dianion chemistry of pyroglutamates: Reaction at C-4 with electrophiles

O, C-Di-lithio di-anions derived from N-substituted pyroglutamic acids react with electrophiles to give C-4 α- substituted products. O, C- Di-lithio di-anions derived from N-substituted pyroglutamic acids react with electrophiles to give C-4 α- substituted products.

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 40; no. 23; pp. 4411 - 4412
Main Authors Dikshit, Dinesh K., Maheshwari, Anjana
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 04.06.1999
Elsevier
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
DIANION CHEMISTRY
ASYMMETRIC-SYNTHESIS
ACETIC-ACID
THIENAMYCIN
Online AccessGet full text

Cover

More Information
Summary:O, C-Di-lithio di-anions derived from N-substituted pyroglutamic acids react with electrophiles to give C-4 α- substituted products. O, C- Di-lithio di-anions derived from N-substituted pyroglutamic acids react with electrophiles to give C-4 α- substituted products.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(99)00759-5