Post Cochlear Implantation Vertigo: Ictal Nystagmus and Audiovestibular Test Characteristics

• Published in: Otology & neurotology Vol. 45; no. 1; p. 65
• Main Authors: Kwok, Belinda Y C, Young, Allison S, Kong, Jonathan H K, Birman, Catherine S, Flanagan, Sean, Greenberg, Simon L, Gibson, William P, Argaet, Emma C, Fratturo, Luke, Pogson, Jacob M, Taylor, Rachael L, Rosengren, Sally M, Halmagyi, G Michael, Welgampola, Miriam S
• Format: Journal Article
• Language: English
• Published: United States 01.01.2024
• ISSN: 1537-4505
• DOI: 10.1097/MAO.0000000000004037

To investigate ictal nystagmus and audiovestibular characteristics in episodic spontaneous vertigo after cochlear implantation (CI). Retrospective and prospective case series. Twenty-one CI patients with episodic spontaneous vertigo after implantation were recruited. Patient-initiated home video-oculography recordings were performed during one or more attacks of vertigo, using miniature portable home video-glasses. To assess canal and otolith function, video head-impulse tests (vHITs) and vestibular-evoked myogenic potential tests were conducted. Nystagmus slow-phase velocities (SPVs), the presence of horizontal direction-changing nystagmus, and post-CI audiovestibular tests. Main final diagnoses were post-CI secondary endolymphatic hydrops (48%) and exacerbation of existing Ménière's disease (29%). Symptomatic patients demonstrated high-velocity horizontal ictal-nystagmus (SPV, 44.2°/s and 68.2°/s in post-CI secondary endolymphatic hydrop and Ménière's disease). Direction-changing nystagmus was observed in 80 and 75%. Two were diagnosed with presumed autoimmune inner ear disease (SPV, 6.6°/s and 172.9°/s). One patient was diagnosed with probable vestibular migraine (15.1°/s).VHIT gains were 0.80 ± 0.20 (lateral), 0.70 ± 0.17 (anterior), and 0.62 ± 0.27 (posterior) in the implanted ear, with abnormal values in 33, 35, and 35% of each canal. Bone-conducted cervical and ocular vestibular-evoked myogenic potentials were asymmetric in 52 and 29% of patients (all lateralized to the implanted ear) with mean asymmetry ratios of 51.2 and 35.7%. Reversible reduction in vHIT gain was recorded in three acutely symptomatic patients. High-velocity, direction-changing nystagmus time-locked with vertigo attacks may be observed in post-CI implant vertigo and may indicate endolymphatic hydrops. Fluctuating vHIT gain may be an additional marker of a recurrent peripheral vestibulopathy.