A Rare Instance of Levofloxacin Induced Myoclonus

Levofloxacin is a widely used fluoroquinolone, mainly as a respiratory antimicrobial agent. It is employed as a second line therapeutic modality in pulmonary tuberculosis as well. The drug has been in use for ages, and is known to be both efficacious and safe. However, it is not free of adverse effe...

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Published inJournal of clinical and diagnostic research Vol. 11; no. 7; pp. FD01 - FD02
Main Authors Kunder, Sushil Kiran, Avinash, A, Nayak, Veena, Tilak, Amod
Format Journal Article
LanguageEnglish
Published India JCDR Research and Publications (P) Limited 01.07.2017
JCDR Research and Publications Private Limited
Subjects
chorea
fluoroquinolones
involuntary movements
Pharmacology Section
Fluoroquinolones
Involuntary movements
Chorea
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Summary:Levofloxacin is a widely used fluoroquinolone, mainly as a respiratory antimicrobial agent. It is employed as a second line therapeutic modality in pulmonary tuberculosis as well. The drug has been in use for ages, and is known to be both efficacious and safe. However, it is not free of adverse effects. The most dangerous ones are those involving the Central Nervous System (CNS). Although rare, levofloxacin can cause involuntary movements like chorea and myoclonus. Here by, we present a case of an elderly male patient who developed reversible myoclonus/chorea after a course of levofloxacin (which was initiated as part of his anti-tubercular therapy) following the development of peripheral neuropathy secondary to isoniazid.
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2017/27005.10189