Binding Capability and Non–biofouling Efficacy of Poly[2‐(methacryloyloxy)ethyl‐4‐pentynoate‐co‐oligo(ethylene Glycol) Methacrylate] Films on Gold Surfaces

We demonstrated the binding capability and non‐biofouling efficacy of biotinylated, poly(MAEP‐co‐OEGMA) films using streptavidin and fibrinogen. The copolymeric films were synthesized on gold substrates without activation or passivation via the surface initiated‐controlled radical polymerization of...

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Published inBulletin of the Korean Chemical Society Vol. 41; no. 2; pp. 223 - 226
Main Authors Kim, Hyungwook, Hong, Seok‐Pyo, Lee, Jungkyu K., Lee, Bong Soo
Format Journal Article
LanguageEnglish
Published Weinheim Wiley‐VCH Verlag GmbH & Co. KGaA 01.02.2020
대한화학회
Subjects
Polymeric coating
SI‐ARGET ATRP
Surface functionalization
“Click” chemistry
화학
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Summary:We demonstrated the binding capability and non‐biofouling efficacy of biotinylated, poly(MAEP‐co‐OEGMA) films using streptavidin and fibrinogen. The copolymeric films were synthesized on gold substrates without activation or passivation via the surface initiated‐controlled radical polymerization of MAEP and OEGMA in five different molar ratios, followed by biotinylation using “click” chemistry. The copolymeric film synthesized with MAEP at a mole fraction of 0.2 exhibited the best performance of surface plasmon resonance.
Bibliography:https://onlinelibrary.wiley.com/doi/abs/10.1002/bkcs.11941
ISSN:1229-5949
0253-2964
1229-5949
DOI:10.1002/bkcs.11941