A CONVENIENT SYNTHESIS OF 4-OXO-4H-QUINOLIZINES

By reacting .alpha.-substituted picolines (1) (or their synthetic equivalents) with .beta.,.beta.-dichloropropenals (4) (or their synthetic equivalents) substituted 1-(2-pyridyl)-4,4-dichloro-1,3-butadienes (6) were produced. Compounds (6) were smoothly cyclized to the corresponding 4-oxo-4H-quinoli...

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Bibliographic Details
Published inHeterocycles Vol. 24; no. 5; pp. 1401 - 1410
Main Authors FORTI, L, GELMI, ML, POCAR, D, VARALLO, M
Format Journal Article
LanguageEnglish
Published Tokyo Japan Inst Heterocyclic Chemistry 01.05.1986
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:By reacting .alpha.-substituted picolines (1) (or their synthetic equivalents) with .beta.,.beta.-dichloropropenals (4) (or their synthetic equivalents) substituted 1-(2-pyridyl)-4,4-dichloro-1,3-butadienes (6) were produced. Compounds (6) were smoothly cyclized to the corresponding 4-oxo-4H-quinolizines (8) bearing substituents in the 1 and/or 3 positions.
ISSN:0385-5414
1881-0942
DOI:10.3987/r-1986-05-1401