Molten salt-assisted synthesis of C-TiN nanocomposites for sensitive dopamine determination

• Published in: Materials letters Vol. 329; p. 133234
• Main Authors: Wang, Chensheng, Li, Weifeng, Long, Yumei
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.12.2022
• Subjects: C-TiN; Dopamine; Molten-salt synthesis; Nanocomposites; Sensors; C-TiN; Dopamine; Sensors; Nanocomposites; Molten-salt synthesis
• ISSN: 0167-577X; 1873-4979
• DOI: 10.1016/j.matlet.2022.133234

•Carbon coupled TiN nanocomposite was prepared by a molten salt method.•C-TiN exhibited enhanced electrocatalytic activity toward dopamine redox.•C-TiN/GCE displayed superior analytic performance for dopamine assay.•The method was successfully applied for dopamine detection in human serum. This work demonstrates a facile molten-salt synthesis of carbon-titanium nitride (C-TiN) nanocomposites. The C-TiN nanoparticles showed excellent electrocatalytic activity and thus were employed for the electrochemical determination of dopamine (DA). By using a differential pulse voltammetry (DPV) method, a C-TiN modified glassy carbon electrode (C-TiN/GCE) presented a high sensitivity (9620 µA·µM·cm−2) in the determination of DA and its detection limit (LOD) was 0.03 µM (S/N = 3). Moreover, the C-TiN/GCE sensor was used to detect DA in human serum, and acceptable recoveries were obtained.