A new glucosamine-containing amphiphilic spin probe

A new, nonionic amphiphilic spin probe for investigating the extracellular matrix close to the cell membrane by EPR spectroscopy has been synthesized and characterized. A pyrrolidine type nitroxide spin-label has been introduced to the third position of a nonionic sugar polar head (glucosamine) bond...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 50; no. 5; pp. 567 - 569
Main Authors Mravljak, Janez, Pečar, Slavko
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 04.02.2009
Elsevier
Subjects
Chemistry
Chemistry, Organic
Glucosamine
Glycocalyx
Nitroxide free radicals
Physical Sciences
Science & Technology
Spin probes
Glucosamine
Glycocalyx
Spin probes
Nitroxide free radicals
Online AccessGet full text

Cover

More Information
Summary:A new, nonionic amphiphilic spin probe for investigating the extracellular matrix close to the cell membrane by EPR spectroscopy has been synthesized and characterized. A pyrrolidine type nitroxide spin-label has been introduced to the third position of a nonionic sugar polar head (glucosamine) bonded to a lipophilic stearic acid acyl chain anchor. The compound is soluble in polar organic solvents such as ethanol and chloroform, but is sparingly soluble in water.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2008.11.075