Teenager with a Primary Renal Lymphoma: A Case Report

We report a case of an 18-year-old male patient who was diagnosed with primary renal lymphoma (PRL) through biopsy findings and imaging studies. The patient presented with clinical manifestations of distal renal tubular acidosis including polyuria, polydipsia, lower limb weakness, involuntary weight...

Full description

Saved in:
Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 12; no. 3; p. e7181
Main Authors Arriola-Montenegro, Liliana, Palacios-Revilla, Cecilia D, Cateriano-Alberdi, Maria Paula, Valdivia-Vega, Renzo P, Arriola-Montenegro, Jose
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 04.03.2020
Cureus
Subjects
Acidosis
Biomarkers
Case reports
Emergency medical care
Immune system
Infectious diseases
Inflammatory diseases
Kidneys
Laboratories
Lupus
Lymphoma
Medical imaging
Metabolism
Nephrology
Oncology
Patients
Pediatrics
Teenagers
Ultrasonic imaging
Urine
renal
b-cell
lymphoma
Online AccessGet full text

Cover

More Information
Summary:We report a case of an 18-year-old male patient who was diagnosed with primary renal lymphoma (PRL) through biopsy findings and imaging studies. The patient presented with clinical manifestations of distal renal tubular acidosis including polyuria, polydipsia, lower limb weakness, involuntary weight loss, asthenia and dyspnea. No personal background or relevant medical history was reported. A kidney biopsy showed high grade immature B-cell lymphoproliferative process (Non-Hodgkin's Lymphoma) with a Ki67 value greater than 90%. Complementary studies excluded primary lymphoid migration sites, which confirmed the diagnosis of PRL. The oncology unit initiated treatment with a combination of medications due to lack of protocols for the specific treatment. Besides the fact that this condition is rare, it also shows a unique symptoms presentation and non-typical findings in imaging methods. Also, it is important to underline the fact that the treatment is not yet specified for such type of cancer and different combinations are needed to control the disease.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.7181