A Rare Case of Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Transforming into Diffuse Large B-Cell Lymphoma

Mucosa-associated lymphoid tissue lymphoma (MALToma) is a low grade B-cell lymphoma that develops from the lungs, intestinal tract, salivary gland, and other organs and is included under extranodal marginal zone lymphoma. When a primary pulmonary MALToma develops from bronchus-associated lymphoid ti...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 9; no. 6; p. e1373
Main Authors Tiruneh, Fasil, Awan, Ahmad, Amin, Raka, Afreen, Samina, Musa, Abdullahi, Davis, Wayne
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 20.06.2017
Cureus
Subjects
Case reports
Internal Medicine
Lymphoma
Oncology
Pulmonology
maltoma
high grade b-cell lymphoma
diffuse large b-cell lymphoma
baltoma
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Summary:Mucosa-associated lymphoid tissue lymphoma (MALToma) is a low grade B-cell lymphoma that develops from the lungs, intestinal tract, salivary gland, and other organs and is included under extranodal marginal zone lymphoma. When a primary pulmonary MALToma develops from bronchus-associated lymphoid tissue (BALT), it is called BALT lymphoma (BALToma). The etiology of MALToma is not clear; however, an association between chronic inflammatory conditions and BALToma has been observed. Transformation of MALToma to high grade lymphoma is very rare. We experienced a case of MALToma that had developed from the lungs in a patient who was undergoing treatment for latent tuberculosis and rapidly transformed into high grade B-cell lymphoma.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.1373