CuI catalyzed sulfamidation of arylboronic acid using TsNBr2 at room temperature

• Published in: Tetrahedron letters Vol. 58; no. 52; pp. 4855 - 4858
• Main Authors: Loukrakpam, Dineshwori Chanu, Phukan, Prodeep
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 27.12.2017; Elsevier
• Subjects: Arylboronic acid; Arylsulfonamide; Chemistry; Chemistry, Organic; CuI; Physical Sciences; Science & Technology; TsNBr2; TsNBr2; CuI; Arylboronic acid; Arylsulfonamide; C-N; METAL-FREE PROTOCOL; PROTEASE INHIBITORS; SULFONAMIDE DERIVATIVES; BORONIC ACIDS; BROMAMINE-T; ANTICONVULSANT ACTIVITY; ARYL HALIDES; FACILE GENERATION; Cul; N-ARYLATION

[Display omitted] •New source for sulfamidation of boronic acid.•New pathway for CN bond formation.•Expeditious process-Short reaction time.•Excellent yield of Aryl sulfonamide.•Works well with a wide range of boronic acids. An expeditious protocol for amidation arylboronic acid has been developed u...