Stimulation of intestinal chromatin template activity by dietary carbohydrates in adult rats

• Published in: Experientia Vol. 39; no. 2; pp. 166 - 167
• Main Authors: Raul, F, Launay, J.F
• Format: Journal Article
• Language: English
• Published: Switzerland 01.01.1983
• Subjects: Animals; Chromatin - metabolism; Dietary Carbohydrates - pharmacology; DNA-Directed RNA Polymerases - metabolism; Escherichia coli - enzymology; Fructose - pharmacology; human nutrition; Jejunum - ultrastructure; nutrition physiology; Rats; Rats, Inbred Strains; Sucrose - pharmacology; Templates, Genetic; Transcription, Genetic - drug effects

Oral administration of a 70% solution of sucrose to starved adult rats resulted 1 h after feeding in a 3.5-fold stimulation of intestinal chromatin template activity assayed in vitro using E. coli RNA polymerase. A similar stimulatory effect was observed with fructose, whereas glucose exhibited a we...