Stimulation of intestinal chromatin template activity by dietary carbohydrates in adult rats

Oral administration of a 70% solution of sucrose to starved adult rats resulted 1 h after feeding in a 3.5-fold stimulation of intestinal chromatin template activity assayed in vitro using E. coli RNA polymerase. A similar stimulatory effect was observed with fructose, whereas glucose exhibited a we...

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Bibliographic Details
Published inExperientia Vol. 39; no. 2; pp. 166 - 167
Main Authors Raul, F, Launay, J.F
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1983
Subjects
Animals
Chromatin - metabolism
Dietary Carbohydrates - pharmacology
DNA-Directed RNA Polymerases - metabolism
Escherichia coli - enzymology
Fructose - pharmacology
human nutrition
Jejunum - ultrastructure
nutrition physiology
Rats
Rats, Inbred Strains
Sucrose - pharmacology
Templates, Genetic
Transcription, Genetic - drug effects
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Summary:Oral administration of a 70% solution of sucrose to starved adult rats resulted 1 h after feeding in a 3.5-fold stimulation of intestinal chromatin template activity assayed in vitro using E. coli RNA polymerase. A similar stimulatory effect was observed with fructose, whereas glucose exhibited a weaker effect, indicating that the nature of the ingested carbohydrate may have a direct effect on the extent of intestinal chromatin template activation.
ISSN:0014-4754
DOI:10.1007/BF01958879