Growth hormone inhibition of tyrosine aminotransferase in primary cultures of rat liver cells

In primary rat hepatocyte cultures, growth hormone was shown to depress tyrosine aminotransferase levels induced with hydrocortisone. Both induction by glucocorticoid and repression by growth hormone could be demonstrated in cultures several days old.

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Bibliographic Details
Published inBiochimica et biophysica acta Vol. 714; no. 1; pp. 170 - 172
Main Authors Shires, Thomas K., Hargrove, James L.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 12.01.1982
Subjects
Animals
Cells, Cultured
Glucocorticoid
Growth Hormone - pharmacology
Growth hormone inhibition
Hydrocortisone - pharmacology
Insulin - pharmacology
Kinetics
Liver - drug effects
Liver - enzymology
Rat liver cell
Rats
Thyroxine - pharmacology
Tyrosine aminotransferase
Tyrosine Transaminase - metabolism
Growth hormone inhibition
Rat liver cell
Tyrosine aminotransferase
Glucocorticoid
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Summary:In primary rat hepatocyte cultures, growth hormone was shown to depress tyrosine aminotransferase levels induced with hydrocortisone. Both induction by glucocorticoid and repression by growth hormone could be demonstrated in cultures several days old.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0304-4165
0006-3002
1872-8006
DOI:10.1016/0304-4165(82)90140-4