Two new lignans from Anemone vitifolia Buch.-Ham. and their anti-inflammatory activity

[Display omitted] •Two new lignans were isolated from whole herb of Anemone vitifolia Buch.-Ham.•Chemical constituent of Anemone vitifolia Buch.-Ham. is rarely investigated.•Their anti-inflammtory activity was also evaluated. Two new lignans (1–2), together with two known lignans (3–4), were isolate...

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Published inPhytochemistry letters Vol. 38; pp. 133 - 135
Main Authors Mou, Lin-Yun, Wu, Hai-Yan, Hu, Li-Jiao, Wei, Min, Li, Jian-Long, Li, Gan-Peng
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.08.2020
Subjects
Anemone vitifolia
Anti-Inflammatory activity
Lignan
Anti-Inflammatory activity
Lignan
Anemone vitifolia
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Summary:[Display omitted] •Two new lignans were isolated from whole herb of Anemone vitifolia Buch.-Ham.•Chemical constituent of Anemone vitifolia Buch.-Ham. is rarely investigated.•Their anti-inflammtory activity was also evaluated. Two new lignans (1–2), together with two known lignans (3–4), were isolated from the whole herb of Anemone vitifolia. The structures were identified based on extensive spectroscopic data analysis and comparison with reported data. All compounds of this plant were reported for the first time. In vitro test, all compounds were evaluated for their anti-inflammatory activity via calculating the production of nitric oxide (NO) in lipopolysaccharide (LPS)-induced mouse macrophage cells-RAW 264.7.
ISSN:1874-3900
1876-7486
DOI:10.1016/j.phytol.2020.06.001