Ectopic low-lying implantation pregnancy: analysis of outcomes depending on gestation age

• Published in: Russian open medical journal Vol. 8; no. 2; p. e0208
• Main Authors: Makukhina, Tatiana B., Makukhina, Viktoriia V.
• Format: Journal Article
• Language: English
• Published: Limited liability company «Science and Innovations» (Saratov) 01.06.2019
• Subjects: antenatal bleeding; cervico-isthmic pregnancy; cesarean scar pregnancy; low-lying implantation pregnancy; pregnancy loss (ectopic pregnancy)
• ISSN: 2304-3415; 2304-3415
• DOI: 10.15275/rusomj.2019.0208

The objective is to define the optimal term of treatment of ectopic low-lying implantation pregnancy (LIP), including cesarean scar pregnancies (CSP) and cervico-isthmic pregnancies (CIP). Material and Methods ― A single-center retrospective study examining the data of 37 patients with CSP and CIP. Gestation age (GA), human chorionic gonadotropin (β-HCG) level, ultrasound protocols, outcomes and follow-up were evaluated. The patients were divided into two groups according to their gestation age (GA) calculated from the last menstrual period, i.e.: up to 55 days inclusively – 1st group, 56 days and more – 2nd group. Results ― Significant difference was found in blood loss and repeated invasive procedures (RIP) numbers between the groups (р=0.010 and р=0.046, respectively). GA>55 days increases the risk of RIP for patients with LIP four times (OR=4.00, 95% CI 0.99-16.15). Conclusion ― Termination of LIP performed in 1-st trimester allows to preserve uterus in all cases. Blood loss and the risk of RIP were significantly lower if LIP termination was performed before 8-th gestational week.