Biosensing using DNA-based structures integrated with nanosheets

• Published in: Microchemical journal Vol. 191; p. 108779
• Main Authors: Ahmadi-Sangachin, Elnaz, Bazzi, Fatima, Xu, Guobao, Hosseini, Morteza
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.08.2023
• Subjects: Biosensing; Detection; DNA-based structures; Nanosheets; ISDA; OxPPD; TWJs; F-PNA; H2O2; RBA; EDC/NHS; SDA; TAMRA; PNP; CDS; VS2; EXPAR; ssDNA; CEA; DNA-based structures; cc-hairpin DNA; SDR; AA; 5ʹ-P-dsDNA; AuNFs; TsDNA; CESA; CVD; RCPs; Ti3C2Tx MXene; FNAs; Detection; VEGF165; CRET; RTB; ThT; FTP; BNNSs; PPD; SA; FLT; SG; COX2; Fc-ssDNAs; FRET; PNPP; Cy3; Cy5; MnO2; CD; LETDA/M; CL; H-GNs; NMM; ECL; BHQ-2; NEL; HIV; ERGO; MoO42; ATP; MCT; MBs; ALP; ITO; sdsDNA; HRP; LIBs; NELRCA; λ exo; HSD; cDNA; ABEI; AgNCs; HBV; PSA; MoS2; HCA; SDDA; Biosensing; HCR; δ-FeOOH; MWCNTs; Sg-GFETs; dsDNA; PCR; CoOOH; g-C3N4; NPC; Nanosheets; IFOs; Nt.BbvCI; LTP; SA-ALP; G4; g-CNQDs; Cd2; TFOs; MNCs; WS2; AuNPs; CA15-3; UO2; rGO; Exo-III; Ti3C2; GSH; Fc; GO; GCE; NrGO; TMD; Bi3Te2; PEC; FAM; MGN; ISDPR; UCNP; TMR; LAMP; OTA
• ISSN: 0026-265X; 1095-9149
• DOI: 10.1016/j.microc.2023.108779

[Display omitted] •Recent works in DNA nanotechnology and nanosheet-based biosensing methods are summarized.•Different types of DNA structures are combined with nanosheets: branched DNA, amplified linear DNA and functional DNA.•Transition metal dichalcogenides nanosheets interact differently with ssDNA compared to dsDNA.•The use of both nanosheets and DNA-based structures enhances biosensor sensitivity, selectivity, and signal amplification. Nanotechnology has rapidly become an attractive field of research, enabling the design of unique, precisely-shaped nanostructures in one, two, and three-dimensional geometries. Investment in this area has proven to be an effective strategy for creating innovative platforms with a wide range of biomedical applications. However, to further enhance the potential of these nanostructures, researchers have explored the integration of natural and synthetic architectures with nanomaterials to achieve specific interactions and functionalities. In this review, we focus on the integration of DNA-based structures with nanosheets, a specific type of nanomaterial, for biosensing applications. This integration has resulted in significant advances, including improved efficiency, selectivity, and specificity of biosensors. We will explore these advances and their potential implications for future biosensing technologies.