Direct solid-phase synthesis of quinoxaline-containing peptides

[Display omitted] The solid-phase synthesis of a series of model dipeptides containing various 3-(quinoxalin-6-yl)alanine analogues is described. The method involves formation of a quinoxaline heterocycle by condensation between an α-dicarbonyl compound and a β-(3,4-diaminophenyl)alanine residue, im...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 46; no. 33; pp. 5525 - 5528
Main Authors Staszewska, Anna, Stefanowicz, Piotr, Szewczuk, Zbigniew
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 15.08.2005
Elsevier
Subjects
4-Amino-3-nitrophenylalanine
Chemistry
Chemistry, Organic
Physical Sciences
Quinoxaline
Science & Technology
Solid-phase peptide synthesis
Unnatural amino acids
Quinoxaline
Solid-phase peptide synthesis
4-Amino-3-nitrophenylalanine
Unnatural amino acids
solid-phase peptide synthesis
ROUTE
4-amino-3-nitroplieiiylalanine
unnatural amino acids
PROTEIN-STRUCTURE
SIDE-CHAIN
COMPLEXES
UNNATURAL AMINO-ACIDS
VERSATILE APPROACH
GENETIC-CODE
DNA
ALKYNYL KETONES
quinoxaline
DERIVATIVES
Online AccessGet full text

Cover

More Information
Summary:[Display omitted] The solid-phase synthesis of a series of model dipeptides containing various 3-(quinoxalin-6-yl)alanine analogues is described. The method involves formation of a quinoxaline heterocycle by condensation between an α-dicarbonyl compound and a β-(3,4-diaminophenyl)alanine residue, immobilized on a solid support.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2005.06.047