Synthesis of enantiomerically pure functionalised trianglamine macrocycles by N-acylation and N-alkylation reactions

The N-alkylation and N-acylation reactions of trianglamine macrocycles are described leading to an efficient synthesis of enantiomerically pure functionalised hexa-amide and hexa-amine trianglamine macrocycles.

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Bibliographic Details
Published inTetrahedron letters Vol. 47; no. 38; pp. 6915 - 6918
Main Authors Kuhnert, Nikolai, Göbel, Daniela, Thiele, Caroline, Renault, Benjamin, Tang, Bing
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 18.09.2006
Elsevier
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
TRIANGLIMINE
Online AccessGet full text
ISSN0040-4039
1873-3581
DOI10.1016/j.tetlet.2006.06.160

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Summary:The N-alkylation and N-acylation reactions of trianglamine macrocycles are described leading to an efficient synthesis of enantiomerically pure functionalised hexa-amide and hexa-amine trianglamine macrocycles.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2006.06.160