Volume and ion regulating renal functions in the big gerbil ( Rhombomys opimus L.) and the water vole ( Arvicola terrestris L.)

• Published in: Comparative biochemistry and physiology. A, Comparative physiology Vol. 72; no. 3; pp. 535 - 539
• Main Authors: Natochin, Yu.V, Ivanova, L.N, Serebryakov, E.P, Podsekaeva, G.V, Pechurkina, N.I, Lavrova, E.A, Lavrinenko, V.A, Melidi, N.N, Nasledova, N.I, Shakhmatova, E.I
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 1982
• Subjects: Absorption; Animals; Arvicolinae - physiology; Electrolytes - metabolism; Female; Gerbillinae - physiology; Kidney - physiology; Male; Osmolar Concentration
• ISSN: 0300-9629
• DOI: 10.1016/0300-9629(82)90119-0

1. 1. After iso-osmotic salt loading (1% NaCl, 1.25% KCl, 0.75% MgCl 2 solutions, each load making up 5% body weight) the water voles excreted 66.2% sodium, 84.4% potassium, 18.8% magnesium over a 4 hr period. The big gerbil excreted 20%, 58.9% and 7.1% respectively over the same period. The volume of the water excreted was greater in the case of the water vole. 2. 2. There were no considerable changes in plasma ion concentration in rodents of the species studied after salt loading. 3. 3. The gerbils and water voles had no significant changes in the renal cortex electrolyte concentrations as a result of isotonic salt loads. The highest sodium cortico-papillar gradient was found in the gerbils when experimenting with the isotonic NaCl loading. It was somewhat lower with the KCl load, and significantly lower with water and MgCl 2 loads. 4. 4. Under the same experimental conditions, no major changes in the papilla sodium concentration were found in the water voles. 5. 5. The concentrations of potassium, calcium and magnesium were practically alike in all zones of the renal tissue of both rodent species, ion loads producing no effect. 6. 6. The comparison of the renal volume and ion regulating function in rodents with different urine osmotic concentration systems proves the independent existence of renal functions. The greater rate of renal fluid and ion excretion in the water voles is coupled with less specific ion regulation.