Intracerebral xenotransplantation: recent findings and perspectives for local immunosuppression

• Published in: Current opinion in organ transplantation Vol. 16; no. 2; p. 190
• Main Authors: Lévêque, Xavier, Cozzi, Emanuele, Naveilhan, Philippe, Neveu, Isabelle
• Format: Journal Article
• Language: English
• Published: United States 01.04.2011
• Subjects: Animals; Brain - immunology; Brain - surgery; Cell Survival; Graft Survival; Humans; Immunosuppressive Agents - therapeutic use; Nerve Regeneration; Neurons - immunology; Neurons - transplantation; Stem Cell Transplantation; Transplantation Tolerance; Transplantation, Heterologous; Treatment Outcome

Cell therapy is a promising strategy for tissue repair in the central nervous system. In this perspective, several cell types are being considered, including allogenic neuroblasts, embryonic stem cells and induced pluripotent stem cells. The use of allogenic neuroblasts as cell source is limited by...