New lanostane-type triterpenoids, inonotsutriols D, and E, from Inonotus obliquus

• Published in: Phytochemistry letters Vol. 4; no. 3; pp. 328 - 332
• Main Authors: Tanaka, Reiko, Toyoshima, Misaki, Yamada, Takeshi
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.09.2011
• Subjects: Hymenochaetaceae; Inonotsutriol D; Inonotsutriol E; Inonotus obliquus; Leukemia; Inonotsutriol D; Inonotus obliquus; Inonotsutriol E; Hymenochaetaceae; Leukemia

New triterpenoids named inonotsutriols D ( 1) and E ( 2) were isolated from I. obliquus. Their structures were determined as lanost-8-ene-3β,22 R,24 R-triol ( 1) and lanost-8-ene-3β,22 R,24 S-triol ( 2). Compound 1 exhibited cytotoxic activity against four cancer cell lines (P388, L1210, HL-60, and...