Convenient preparation of (E)-3-arylidene-4-diazopyrrolidine-2,5-diones in array format

[Display omitted] A practically convenient synthesis of (E)-3-arylidene-4-diazopyrrolidine-2,5-diones from N-substituted maleimides via the Wittig reaction and the Regitz diazo transfer has been developed. In all 26 cases studied, only one chromatographic purification was required with no need for a...

Full description

Saved in:
Bibliographic Details
Published inMendeleev communications Vol. 31; no. 1; pp. 36 - 38
Main Authors Chupakhin, Evgeny G., Kantin, Grigory P., Dar’in, Dmitry V., Krasavin, Mikhail
Format Journal Article
LanguageEnglish
Published AMSTERDAM Elsevier B.V 01.01.2021
Elsevier
Subjects
Chemistry
Chemistry, Multidisciplinary
diazo compounds
diazo transfer
maleimides
Michael acceptors
parallel synthesis
Physical Sciences
privileged structures
Science & Technology
Wittig reaction
Wittig reaction
diazo transfer
Michael acceptors
privileged structures
diazo compounds
maleimides
parallel synthesis
Online AccessGet full text

Cover

More Information
Summary:[Display omitted] A practically convenient synthesis of (E)-3-arylidene-4-diazopyrrolidine-2,5-diones from N-substituted maleimides via the Wittig reaction and the Regitz diazo transfer has been developed. In all 26 cases studied, only one chromatographic purification was required with no need for aqueous workup, which makes this protocol amenable to producing the emerging class of diazo compounds in parallel format.
ISSN:0959-9436
1364-551X
DOI:10.1016/j.mencom.2021.01.010