Radiation Recall in a Patient with Intrahepatic Cholangiocarcinoma: Case Report and a Literature Review

Radiation recall dermatitis (RRD) is a rare and poorly understood phenomenon, constituting an inflammatory skin reaction to a previously irradiated area of skin following the administration of certain agents, usually chemotherapy. Our patient developed RRD 66 years after receiving radiation therapy;...

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Published inCurēus (Palo Alto, CA) Vol. 11; no. 6; p. e5020
Main Authors Bahaj, Waled, Ya'qoub, Lina, Toor, Muhammad, Masood, Ashiq
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 27.06.2019
Cureus
Subjects
Abdomen
Breast cancer
Cancer therapies
Case reports
Chemotherapy
Cholangiocarcinoma
Dermatitis
Drug dosages
Gallbladder
Gallbladder cancer
Histamine
NMR
Nuclear magnetic resonance
Oncology
Patients
Radiation Oncology
Radiation therapy
Ultrasonic imaging
United States > US
Kansas City Missouri
recall dermatitis
rash
gallbladder cancer
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Summary:Radiation recall dermatitis (RRD) is a rare and poorly understood phenomenon, constituting an inflammatory skin reaction to a previously irradiated area of skin following the administration of certain agents, usually chemotherapy. Our patient developed RRD 66 years after receiving radiation therapy; to the best of our knowledge, this is the longest reported period in the literature. The mainstay of therapy is to withhold the agent that elicited the adverse reaction, followed by symptomatic management. Subjecting patients to further chemotherapy can provoke another episode of RRD. Therefore, clinical judgment in this regard is usually recommended.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.5020