Smoking cessation in clinical practice: predictors of six-month continuous abstinence in a sample of Greek smokers

• Published in: Primary care respiratory journal Vol. 17; no. 1; pp. 32 - 38
• Main Authors: Boutou, Afroditi K, Tsiata, Eleni A, Pataka, Athanasia, Kontou, Paschalina K, Pitsiou, Georgia G, Argyropoulou, Paraskevi
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.03.2008
• Subjects: Adult; Bupropion - therapeutic use; Case-Control Studies; Female; Follow-Up Studies; Greece; Humans; Male; Middle Aged; Nicotine - adverse effects; Nicotine - therapeutic use; Nicotinic Agonists - adverse effects; Nicotinic Agonists - therapeutic use; Original Research; Sleep Initiation and Maintenance Disorders - chemically induced; Smoking - drug therapy; Smoking Cessation - methods; Smoking Cessation - psychology; Treatment Outcome; Greece
• ISSN: 1471-4418; 1475-1534
• DOI: 10.3132/pcrj.2008.00009

To identify the predictors of six-month continuous abstinence among Greek smokers treated in a Smoking Cessation Clinic, emphasising the role of sleep disturbance on the outcome. A nested case-control design was used. Patients who attended the Smoking Cessation Clinic between November 2004 and October 2005, and who completed six months of follow-up, constituted the final study population (N=285). The patients were separated into two groups - those who managed to quit smoking and those who didn't. The cessation method included pharmacotherapy, one-to- one behavioral counselling, and follow-up by telephone communication. Among various baseline characteristics examined, multivariate regression analysis indicated that the time to first cigarette after awakening, and use of bupropion, independently predicted abstinence, while awakening during the night was negatively associated with abstinence. These multivariate factors, which can positively or negatively affect the outcome, should be taken into account so that smoking cessation treatment can be individualised.