Comparison of MRI outcomes of uterine artery embolization for uterine leiomyoma using tris-acryl gelatin microspheres, polyvinyl alcohol spheres, and polyvinyl alcohol particles

• Published in: Journal of computer assisted tomography Vol. 32; no. 3; p. 356
• Main Authors: Galvez, Jorge A, McCarthy, Shirley, Weinreb, Jeffrey, Zelterman, Daniel, White, Robert I, Pollak, Jeffrey, Tal, Michael G
• Format: Journal Article
• Language: English
• Published: United States 01.05.2008
• Subjects: Acrylic Resins - therapeutic use; Embolization, Therapeutic; Female; Gelatin - therapeutic use; Humans; Leiomyoma - diagnosis; Leiomyoma - therapy; Magnetic Resonance Imaging; Polyvinyl Alcohol - therapeutic use; Uterine Neoplasms - diagnosis; Uterine Neoplasms - therapy; Uterus - blood supply
• ISSN: 0363-8715
• DOI: 10.1097/RCT.0b013e3180de4968

Comparison of recurrence of magnetic resonance imaging (MRI) enhancement of uterine fibroids treated with uterine artery embolization (UAE) among embolic agents: polyvinyl alcohol (PVA), spherical PVA (SPVA), and tris-acryl gelatin microspheres (GM). Pre/post-UAE gadolinium-enhanced MRIs were evaluated for residual enhancement of fibroids after UAE. Data were analyzed using 2-tail Fisher exact test to determine the likelihood of recurrence of enhancement post-UAE among embolic agents. One hundred one women underwent UAE. A total of 24 (41%) of 59 embolized with PVA, 18 (75%) of 24 with SPVA, and 4 (22%) of 18 with GM showed residual enhancement in some or all fibroids. Statistically significant differences in presence of residual enhancement on follow-up were found between SPVA and PVA (P = 0.0072), and SPVA and GM (P = 0.0015), but not between PVA and GM (P = 0.1756). Patients embolized with SPVA have a higher risk of having residual enhancement on follow-up MRI than those embolized with PVA or GM.