Inferring genetic ancestry from cancer sequencing data

Genetic ancestry is an important biological determinant of cancer health disparities that is not captured by self-identified race and ethnicity (SIRE). Belleau et al. recently developed a systematic computational approach to infer genetic ancestry from cancer-derived molecular data from different ge...

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Bibliographic Details
Published inTrends in genetics Vol. 39; no. 6; pp. 431 - 432
Main Authors Arora, Kanika, Berger, Michael F.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.06.2023
Subjects
ancestry
Ethnicity
Genome
Genomics
Humans
Neoplasms - genetics
tumor sequencing
tumor sequencing
ancestry
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Summary:Genetic ancestry is an important biological determinant of cancer health disparities that is not captured by self-identified race and ethnicity (SIRE). Belleau et al. recently developed a systematic computational approach to infer genetic ancestry from cancer-derived molecular data from different genomic and transcriptomic profiling assays, creating opportunities to interrogate population-scale data sets.
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ISSN:0168-9525
DOI:10.1016/j.tig.2023.03.003