Preoperative chemotherapy and intraoperative radiofrequency ablation for unresectable solid pseudopapillary tumor of the pancreas

• Published in: Journal of pediatric hematology/oncology Vol. 29; no. 12; p. 851
• Main Authors: Hah, Jeong Ok, Park, Won Kyu, Lee, Nam Hyuk, Choi, Joon Hyuk
• Format: Journal Article
• Language: English
• Published: United States 01.12.2007
• Subjects: Adult; Antineoplastic Agents - therapeutic use; Carcinoma, Papillary - drug therapy; Carcinoma, Papillary - surgery; Carcinoma, Papillary - therapy; Catheter Ablation; Cisplatin - therapeutic use; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Pancreatic Neoplasms - drug therapy; Pancreatic Neoplasms - surgery; Pancreatic Neoplasms - therapy; Tomography, X-Ray Computed; Treatment Outcome
• ISSN: 1077-4114
• DOI: 10.1097/MPH.0b013e318158159c

Solid pseudopapillary tumor (SPT) is rare primary tumor of the pancreas with low malignant potential affecting adolescent or young women. Radical surgical resection is the definitive treatment for long-term survival even in the patients with metastases. We report a case of 14-year-old girl who presented with unresectable SPT of the pancreas. She received preoperative chemotherapy with cisplatinum, ifosfamide, etoposide, and vincristine followed by intraoperative radiofrequency ablation of metastatic liver lesions with surgical resection of the primary tumor successfully. We demonstrate that all attempts should be made to resect or ablate the primary as well as the metastatic lesions for long-term survival.